Scientific Publications

niostem’s results from its first pilot study with the niostem headset were presented to a scientific audience of dermatologists and hair experts at the world renown Annual Meeting of the Society for Investigative Dermatology - SID 2024 Annual Meetingin May 2024, Dallas - Texas - USA. This meeting brings together leading dermatologists and doctors to share innovations in the fields of dermatology.

15 May, 2024

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Dr. Chacón-Martínez was invited to give a talk about the niostem technology at the prestigious AMWC 2024 in Monaco (March 29th). The scientific results from the first pilot study with the niostem headset were presented to a scientific audience of hair and skin experts. The AMWC 2024 congress brings together leading researchers and doctors to share innovations in the fields of anti-aging and aesthetic medicine.

14 March 2024

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Dr Carlos Chacón’s research continues to be picked up by the scientific world. Carlos co-authored this article on the identification of a key regulator of sebaceous gland homeostasis.

14 April 2021

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Journal of Cell science publishes co-authored article of Dr Carlos Chacón’s research into stem cell fate

1 May 2021

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An international team of researchers from the Universities of Cologne and Helsinki and the Max Planck Institute for Biology of Ageing have discovered that the ability of stem cells to proliferate and renew organs is regulated by the stiffness of the surrounding tissue. This finding may have implications for improving the regeneration of aged tissue.

8 July 2021

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New findings identify how changes in hair stem cells' micro-environment control the age-related decline in their regenerative abilities. - Nature Cell Biology publishes papers of the highest quality from all areas of cell biology

8 July 2021

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‘Hair loss might be prevented by regulating stem cell metabolism’. ScienceDaily features breaking news about the latest discoveries in science

13 October 2020

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Scientists discover factors that control hair follicle stem cell fate reversibility and long-term maintenance of the hair follicle.

6 October 2020

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A team of researchers discover a mechanism that prevents hair loss: hair follicle stem cells are the key.

28 September 2020

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Self-Activated Electrical Stimulation for Effective Hair Regenerationvia a Wearable Omnidirectional Pulse Generator

Here, a wearable, universal motion-activated electric stimulation tool was created that can efficiently encourage hair regeneration by arbitrary body motions. A notable improvement in hair regeneration was observed in Sprague-Dawley rats and naked mice. When the device was used in place of traditional pharmaceutical treatments, Sprague-Dawley rats showed greater hair shaft length and higher hair follicle density.

10 September 2019

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Dr Carlos Chacón authors a literature review on the study of the signalling that calls stem cells into action to regenerate damaged tissue - Signalling in the stem cell niche: regulating cell fate, function and plasticity

1 August 2018

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Dr Carlos Chacón & colleagues at the Max Planck Institute for Biology of Ageing, file a patent on a Hair Follicle Stem Cell (HFSC) culture system that furthers the field of regenerative science.

17 January 2017

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The exciting invention by Dr Carlos Chacón of a method that allows for studies on hair follicle stem cell fate leads to a deepening understanding of stem cells and their regenerative abilities.

17 January 2017

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“Growing hair follicle stem cells with our method is likely to have important implications in regenerative medicine. Modern medicine is already able to grow and transplant skin, but this is hairless. Maybe we could help bald men to regrow hair", says Chacón.

19 December 2016

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Pulsed electrostatic fields (ETG) to reduce hair loss in women undergoing chemotherapy for breast carcinoma: a pilot study

This study shows encouraging results in an area where no other appropriate treatment is available Reducing alopecia, secondary to chemotherapy has the potential to increase CMF treatment compliance, enhance patient self-esteem, and improve overall quality of life during this stressful period.

May-Jun 2002

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Electrotrichogenesis: further evidence of efficacy and safety on extended use

These data represent a subset of data from the original 36-week study conducted by Maddin et al., which was in itself a preliminary study of a pulsed electrical stimulation device in male subjects alone. The extension phase of this study, which is summarized here, was undertaken to gather data on longer-term efficacy and safety and to study clinical effects in control subjects who were then switched to active treatment. Thirteen subjects had active treatment for 70 weeks, and 14 subjects were included in the crossover group, which had sham treatment for 36 weeks followed by active treatment for 30 additional weeks. On average, terminal hair counts increased from 82 to 276 in the active treatment group. Among those in the crossover group, a mild increase, from 124 to 160, was observed during the sham treatment period and a more notable increase, from 160 to 249, occurred during the subsequent active treatment period. The results presented here provide evidence of the efficacy and safety of this device during extended use; however, the generalizability of these findings is limited by the small subset of subjects for whom complete data are available.

December 1992

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The biological effects of a pulsed electrostatic field with specific reference to hair. Electrotrichogenesis

This comparative, controlled study demonstrates the positive biologic effect on hair regrowth of a pulsed electrical field administered according to a regularized treatment schedule over 36 weeks. Mean hair count comparisons within the groups significantly favor the treatment group, which exhibited a 66.1% hair count increase over baseline. The control group increase over baseline was 25.6%. It is notable also that 29 of the 30 treatment subjects (96.7%) exhibited regrowth or no further hair loss. The process is without side effects and untoward reactions. The rationale of this phenomenon is unclear but is considered to be due to an electrophysiologic effect on the quiescent hair follicle, similar to that documented with respect to bone fracture and soft tissue repair enhancement. The electrical pulse may cause increased cell mitosis through calcium influx, involving both the hair follicle sheath and dermal papilla cells.

Jul-Aug 1990

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